منابع مشابه
Urinary biomarkers of oxidative status in a clinical model of oxidative assault.
BACKGROUND We used doxorubicin-based chemotherapy as a clinical model of oxidative assault in humans. METHODS The study recruited newly diagnosed breast cancer patients (n = 23). Urine samples were collected immediately before (T0) and at 1 hour (T1) and 24 hours (T24) after i.v. administration of treatment. Measurements included allantoin and the isoprostanes iPF(2alpha)-III, iPF(2alpha)-VI,...
متن کاملBiomarkers of oxidative status: missing tools in conservation physiology
Recent ecological studies have shown that oxidative status could have a significant impact on fitness components in wild animals. Not only can oxidative status reflect the environmental conditions that animals experience, but it can also predict their chances of reproduction and survival in the future in their natural habitat. Such important characteristics make markers of oxidative status info...
متن کاملOxidative status parameters in children with urinary tract infection
INTRODUCTION Urinary tract infection (UTI) is one of the most common bacterial infectious diseases in children. The aim of this study was to determine the total prooxidant and antioxidant capacity of children with UTI, as well as changes of oxidative status parameters according to acute inflammation persistence and acute kidney injury (AKI) development. MATERIALS AND METHODS The patients enro...
متن کاملDiscovery of urinary biomarkers.
A myriad of proteins and peptides can be identified in normal human urine. These are derived from a variety of sources including glomerular filtration of blood plasma, cell sloughing, apoptosis, proteolytic cleavage of cell surface glycosylphosphatidylinositol-linked proteins, and secretion of exosomes by epithelial cells. Mass spectrometry-based approaches to urinary protein and peptide profil...
متن کاملUrinary Biomarkers in Glomerulonephritis
A biomarker refers to a biologic, biochemical or molecular event that can be assayed qualitatively and quantitatively by laboratory techniques. The level of biomarkers should correlate with disease pathogenesis or activity. Biomarker discovery for kidney diseases is currently an active area of investigation. Today golden standard for diagnosis and for evaluation of treatment results is kidney b...
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ژورنال
عنوان ژورنال: Clinica Chimica Acta
سال: 2012
ISSN: 0009-8981
DOI: 10.1016/j.cca.2012.06.012